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Gregory A Light Selected Research

Cognitive Training

1/2022The viability of the frequency following response characteristics for use as biomarkers of cognitive therapeutics in schizophrenia.
11/2021Evaluation of the frequency following response as a predictive biomarker of response to cognitive training in schizophrenia.
11/2021Contextualizing the road to recovery: A novel method of assessing outcome trajectories in clinical trials.
10/2021Central auditory processing deficits in schizophrenia: Effects of auditory-based cognitive training.
4/2021Auditory discrimination and frequency modulation learning in schizophrenia patients: amphetamine within-subject dose response and time course.
11/2020Gamma oscillations predict pro-cognitive and clinical response to auditory-based cognitive training in schizophrenia.
1/2020Oscillatory biomarkers of early auditory information processing predict cognitive gains following targeted cognitive training in schizophrenia patients.
1/2019Verbal learning deficits associated with increased anticholinergic burden are attenuated with targeted cognitive training in treatment refractory schizophrenia patients.
1/2019Divergence of subjective and performance-based cognitive gains following cognitive training in schizophrenia.
1/2019Neurophysiologic measures of target engagement predict response to auditory-based cognitive training in treatment refractory schizophrenia.
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Gregory A Light Research Topics

Disease

60Schizophrenia (Dementia Praecox)
01/2022 - 06/2004
11Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 09/2013
8Cognitive Dysfunction
01/2021 - 07/2005
3Alzheimer Disease (Alzheimer's Disease)
01/2022 - 07/2005
3Treatment-Resistant Schizophrenia
01/2019 - 12/2018
2Mental Disorders (Mental Disorder)
03/2022 - 12/2019
2Neurodevelopmental Disorders
01/2022 - 01/2014
2Brain Diseases (Brain Disorder)
12/2020 - 01/2014
1Abdominal Pain (Pain, Abdominal)
01/2022
1Diarrhea
01/2022
1Fatigue
01/2022
1Headache (Headaches)
01/2022
1Nausea
01/2022
1Dementia (Dementias)
01/2021
1Hypoxia (Hypoxemia)
01/2020
1Symptom Flare Up
12/2019
1Bipolar Disorder (Manic Depressive Psychosis)
11/2015

Drug/Important Bio-Agent (IBA)

26Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2009
8Antipsychotic Agents (Antipsychotics)IBA
01/2022 - 06/2004
6Memantine (Namenda)FDA Link
01/2021 - 01/2016
4Pharmaceutical PreparationsIBA
04/2021 - 01/2016
4Amphetamine (Amfetamine)FDA LinkGeneric
04/2021 - 01/2017
4Biological ProductsIBA
12/2019 - 01/2007
2Donepezil (Aricept)FDA LinkGeneric
01/2022 - 07/2005
2Cholinergic Antagonists (Anticholinergics)IBA
01/2021 - 01/2019
1Adenosine Monophosphate (AMP)IBA
01/2022
1Glutamate Receptors (Glutamate Receptor)IBA
01/2022
1Cholinergic Agents (Cholinergics)IBA
01/2022
1Muscarinic M1 ReceptorIBA
01/2022
1Sp4 Transcription FactorIBA
01/2022
1Dopamine D1 Receptors (Dopamine D1 Receptor)IBA
01/2021
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2020
1ParvalbuminsIBA
12/2020
1gamma-Aminobutyric Acid (GABA)IBA
12/2020
1Aminobutyrates (Aminobutyric Acid)IBA
12/2020
1Oxygen (Dioxygen)IBA
01/2020
1Psychotropic Drugs (Psychoactive Drugs)IBA
12/2019
1bis(p-chlorophenyl)acetic acid (DDA)IBA
01/2019
1Dextroamphetamine (Dexedrine)FDA LinkGeneric
01/2018
1Therapeutic UsesIBA
01/2017
1KetamineFDA LinkGeneric
01/2016
1N-Methylaspartate (NMDA)IBA
01/2016
1Proteins (Proteins, Gene)FDA Link
11/2015
1Transcription Factors (Transcription Factor)IBA
11/2015
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
04/2015
1salicylhydroxamic acid (SHAM)IBA
12/2013
1Glutamic Acid (Glutamate)FDA Link
09/2011
1DNA (Deoxyribonucleic Acid)IBA
02/2008
1Risperidone (Risperdal Consta)FDA LinkGeneric
09/2007
1Haloperidol (Haldol)FDA LinkGeneric
09/2007
1Olanzapine (Zyprexa)FDA Link
09/2007
1Cholinesterase Inhibitors (Anticholinesterases)IBA
07/2005

Therapy/Procedure

17Cognitive Training
01/2022 - 04/2016
8Therapeutics
03/2022 - 07/2005
2Electrodes (Electrode)
01/2021 - 10/2012
1Precision Medicine
01/2018
1Drug Therapy (Chemotherapy)
06/2004